After a collision with teammate Robin Gosens at Hoffenheim on November 8, Karius was examined for bruising to his upper body and face. Schalke said he should be able to resume training soon.
Karius made several saves to keep Schalke in contention during a 1-0 home defeat to Mainz. The club named him man of the match, although he was disappointed with the result.
Ahead of the Mainz match, Karius discussed reaching 100 Bundesliga appearances the previous matchday. He said Schalke were working to balance defensive stability with creating chances.
Karius signed a new contract running to June 30, 2028. He had helped Schalke win promotion with 13 clean sheets across 30 league appearances in the 2025/26 season.