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Anna O’Brien

Anna O’Brien, known as Glitter + Lazers, shares plus-size fashion, travel and everyday life, and brings a patient’s perspective to The Medical Detectives podcast.

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Latest

Anna’s happenings, collected from public sources, plus her backstory and Starbook, where fans write.

Known for

Overview

Known online as
Glitter + Lazers
Grew up
Suburbs of Cleveland, Ohio
Before creating
Technology product manager
Breakout
YouTube Shorts helped her reach nearly 100 million monthly views in January 2022

Mini bio

How it started.

Anna grew up in the suburbs of Cleveland and worked in technology as a product manager. She began sharing fashion casually on Instagram, without planning to turn it into a career. In an interview with The Newsette, she described her earlier work at Sprinklr, building software for content strategy.

Finding her audience.

Her early YouTube work mixed clothing hauls with conversations about fat-shaming. After she began posting YouTube Shorts in June 2021, her channel added more than 500,000 subscribers and reached nearly 100 million monthly views in January 2022. She told Tubefilter that short videos were also bringing viewers to her longer work.

Beyond the outfit.

Her 2018 book, A Life Full of Glitter, combines personal stories with ideas about optimism and self-acceptance. In 2025 she began co-hosting The Medical Detectives with orthopedic surgeon Dr. Erin Nance, sharing patients’ stories and asking questions from her own perspective as a patient.

Making room for fans.

In her 2025 News Creator Corps essay, Anna described community as central to her career. She recalled organizing a restaurant fundraiser after Texas floods and working with followers to support a women’s shelter, teachers and children.

Creditschronological, newest first

Podcasts

Books

Quotes

Luck creates viral moments; communities build careers.Anna O’Brien, News Creator Corps

From her September 2025 essay about building relationships with fans online and offline.

Trivia

  1. Her dog Data’s name is a nod to her former work with information and analytics.
  2. Her website calls her a “plus size Carmen San Diego” because of her love of travel.
  3. She has a master’s degree in Quantitative Methods in the Social Sciences from Columbia University.

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